访问量:   最后更新时间:2023-2-28

栾合密

55
教师拼音名称:Luan hemi
职称:教授
所属院系:生物医药学院
其他联系方式

邮箱:luanhm@gdut.edu.cn

科学研究
当前位置: 中文主页 > 科学研究
研究论文

     

    研究论文


    -- 2024


    Qi Z, Cao Y, Li D, Wu C, Wu K, Song Y, Huang Z, Luan H, Meng X, Yang Z, Cai Z. Nontarget Analysis of Legacy and Emerging PFAS in a Lithium-Ion Power Battery Recycling Park and Their Possible Toxicity Measured Using High-Throughput Phenotype Screening. Environ Sci Technol. 2024 Aug 13;58(32):14530-14540. doi: 10.1021/acs.est.4c03552.



    images_large_es4c03552_0005.jpeg




    Wang, X.; Wang, B.; Ji, F.; Yan, J.; Fang, J.; Zhang, D.; Xu, J.; Ji, J.; Hao, X.; Luan, H. Discovery of plasma biomarkers for Parkinson's disease diagnoses based on metabolomics and lipidomics. Chinese Chemical Letters 2024, 109653.


    Luan H, Chen S, Lian J, Zhao B, Xu X, Chen Y, Yang Y, Jiang Z, Qi M, Liu J, Zhang W, Luan T, Hong X. Biofluorescence imaging-guided spatial metabolic tracing: In vivo tracking of metabolic activity in circulating tumor cell-mediated multi-organ metastases. Talanta. 2024 Aug 10;280:126696. doi: 10.1016/j.talanta.2024.126696.


    1-s2.0-S0039914024010750-ga1_lrg.jpg



    -- 2023

    Wang, X.; Hao, X.; Yan, J.; Xu, J.; Hu, D.; Ji, F.; Zeng, T.; Wang, F.; Wang, B.; Fang, J. Urine biomarkers discovery by metabolomics and machine learning for Parkinson's disease diagnoses. Chinese Chemical Letters 202334 (10), 108230.

    Luan, H.; Li, X.; Zhang, W.; Luan, T. Thermal proteome profiling unveils protein targets of deoxycholic acid in living neuronal cells. Advanced Biotechnology 20231 (4), 7.






    Luan, H.; Chen, S.; Zhao, L.; Liu, S.; Luan, T. Precise lipidomics decipher circulating ceramide and sphingomyelin cycle associated with the progression of rheumatoid arthritis. Journal of Proteome Research 202322 (12), 3893-3900.


    images_medium_pr3c00574_0001.gif


    Luan, H.; Cai, Z. Introduction to artificial intelligence and machine learning in environmental science. Environmental Science: Advances 20232(9), 1149-1150.


    Get-2.jpeg


    Chen, S.; Li, X.; Liu, S.; Zhao, L.; Zhang, W.; Xiong, Z.; Luan, H. Rapid, sensitive, and high-throughput quantification of broad serological ceramides by using isotope dilution liquid chromatography-negative ion electrospray tandem mass spectrometry. Analytical and Bioanalytical Chemistry 2023415 (5), 801-808.


    -- 2022

    Luan, H. Machine learning for screening active metabolites with metabolomics in environmental science. Environmental Science: Advances 20221 (5), 605-611.


    d2va00107a-f1.gif


    Luan, H.; Zhao, H.; Li, J.; Zhou, Y.; Fang, J.; Liu, H.; Li, Y.; Xia, W.; Xu, S.; Cai, Z. Research Article Machine Learning for Investigation on Endocrine-Disrupting Chemicals with Gestational Age and Delivery Time in a Longitudinal Cohort. RESEARCH 20212021.


    9873135.fig.001.jpg



    Luan, H.; Gu, W.; Li, H.; Wang, Z.; Lu, L.; Ke, M.; Lu, J.; Chen, W.; Lan, Z.; Xiao, Y. Serum metabolomic and lipidomic profiling identifies diagnostic biomarkers for seropositive and seronegative rheumatoid arthritis patients. Journal of translational medicine 202119, 1-10.

    Zhao, H.; Li, H.; Zheng, Y.; Zhu, L.; Fang, J.; Xiang, L.; Xu, S.; Zhou, Y.; Luan, H.; Xia, W. Association of altered serum acylcarnitine levels in early pregnancy and risk of gestational diabetes mellitus. Science China Chemistry 202063, 126-134.

    Luan, H.; Jiang, X.; Ji, F.; Lan, Z.; Cai, Z.; Zhang, W. CPVA: a web-based metabolomic tool for chromatographic peak visualization and annotation. Bioinformatics 202036 (12), 3913-3915.

    Li, H.; Xu, R.; Yang, L.; Luan, H.; Chen, S.; Chen, L.; Cai, Z.; Tian, R. Combinatory data-independent acquisition and parallel reaction monitoring method for deep profiling of gangliosides. Analytical Chemistry 202092 (15), 10830-10838.


    -- 2019

    Shi, J.; Xiang, L.; Luan, H.; Wei, Y.; Ren, H.; Chen, P. The health concern of polychlorinated biphenyls (PCBs) in a notorious e-waste recycling site. Ecotox Environ Safe 2019186, 109817.

    Luan, H.; Wang, X.; Cai, Z. Mass spectrometry‐based metabolomics: Targeting the crosstalk between gut microbiota and brain in neurodegenerative disorders. Mass spectrometry reviews 201938 (1), 22-33.

    Li, J.; Xia, W.; Wu, C.; Zhao, H.; Zhou, Y.; Wei, J.; Ji, F.; Luan, H.; Xu, S.; Cai, Z. Variations of phthalate exposure and metabolism over three trimesters. Environmental Pollution 2019251, 137-145.

    Ji, F.; Wei, J.; Luan, H.; Li, M.; Cai, Z. Study of metabolic disorders associated with BDE-47 exposure in Drosophila model by MS-based metabolomics. Ecotox Environ Safe 2019184, 109606.

    Ji, F.; Sreenivasmurthy, S. G.; Wei, J.; Shao, X.; Luan, H.; Zhu, L.; Song, J.; Liu, L.; Li, M.; Cai, Z. Study of BDE-47 induced Parkinson’s disease-like metabolic changes in C57BL/6 mice by integrated metabolomic, lipidomic and proteomic analysis. Journal of hazardous materials 2019378, 120738.


    -- 2018

    Zhao, H.; Li, H.; Chung, A. C. K.; Xiang, L.; Li, X.; Zheng, Y.; Luan, H.; Zhu, L.; Liu, W.; Peng, Y. Large-scale longitudinal metabolomics study reveals different trimester-specific alterations of metabolites in relation to gestational diabetes mellitus. Journal of proteome research 201818 (1), 292-300.

    Xiang, L.; Zhang, H.; Wei, J.; Tian, X. Y.; Luan, H.; Li, S.; Zhao, H.; Cao, G.; Chung, A. C.; Yang, C. Metabolomics studies on db/db diabetic mice in skeletal muscle reveal effective clearance of overloaded intermediates by exercise. Analytica Chimica Acta 20181037, 130-139.

    Luan, H.; Ji, F.; Chen, Y.; Cai, Z. statTarget: A streamlined tool for signal drift correction and interpretations of quantitative mass spectrometry-based omics data. Analytica chimica acta 20181036, 66-72.

    Luan, H.; Ji, F.; Chen, Y.; Cai, Z. Quality control-based signal drift correction and interpretations of metabolomics/proteomics data using random forest regression. Biorxiv 2018, 253583.


    --2017

    Luan, H.; Yang, L.; Ji, F.; Cai, Z. PCI-GC–MS–MS approach for identification of non-amino organic acid and amino acid profiles. Journal of Chromatography B 20171047, 180-184.

    Luan, H. HKBU Institutional Repositor y. Mass spectrometry 20178, 1-2017.

    Luan, H. Mass spectrometry based metabolomics for biomarkers of Parkinson's disease. 2017.

    Ji, F.; Luan, H.; Huang, Y.; Cai, Z.; Li, M. MS-based metabolomics for the investigation of neuro-metabolic changes associated with BDE-47 exposure in C57BL/6 mice. Journal of Analysis and Testing 20171 (3), 233-244.


    -- 2016

    Yang, L.; Li, J.; Lai, J.; Luan, H.; Cai, Z.; Wang, Y.; Zhao, Y.; Wu, Y. Placental transfer of perfluoroalkyl substances and associations with thyroid hormones: Beijing prenatal exposure study. Sci Rep-Uk 20166 (1), 21699.

    Wang, S.; Chen, X.; Luan, H.; Gao, D.; Lin, S.; Cai, Z.; Liu, J.; Liu, H.; Jiang, Y. Matrix‐assisted laser desorption/ionization mass spectrometry imaging of cell cultures for the lipidomic analysis of potential lipid markers in human breast cancer invasion. Rapid Commun Mass Sp 201630 (4), 533-542.

    Luan, H.; Meng, N.; Liu, P.; Fu, J.; Chen, X.; Rao, W.; Jiang, H.; Xu, X.; Cai, Z.; Wang, J. Non-targeted metabolomics and lipidomics LC–MS data from maternal plasma of 180 healthy pregnant women. Gigascience 20154 (1), s13742-13015-10054-13749.

    Luan, H.; Meng, N.; Liu, P.; Feng, Q.; Lin, S.; Fu, J.; Davidson, R.; Chen, X.; Rao, W.; Chen, F. Correction to “Pregnancy-Induced Metabolic Phenotype Variations in Maternal Plasma”. Journal of proteome research 201514 (7), 3005-3005.

    Luan, H.; Liu, L.-F.; Tang, Z.; Zhang, M.; Chua, K.-K.; Song, J.-X.; Mok, V. C.; Li, M.; Cai, Z. Comprehensive urinary metabolomic profiling and identification of potential noninvasive marker for idiopathic Parkinson’s disease. Sci Rep-Uk 20155 (1), 13888.

    Luan, H.; Liu, L.-F.; Tang, Z.; Mok, V.; Li, M.; Cai, Z. Elevated excretion of biopyrrin as a new marker for idiopathic Parkinson's disease. Parkinsonism Relat Disord 201521 (11), 1371-1372.

    Luan, H.; Liu, L.-F.; Meng, N.; Tang, Z.; Chua, K.-K.; Chen, L.-L.; Song, J.-X.; Mok, V. C.; Xie, L.-X.; Li, M. LC–MS-based urinary metabolite signatures in idiopathic Parkinson’s disease. Journal of proteome research 201514 (1), 467-478.

    Su, L.; Huang, Y.; Zhu, Y.; Xia, L.; Wang, R.; Xiao, K.; Wang, H.; Yan, P.; Wen, B.; Cao, L. Discrimination of sepsis stage metabolic profiles with an LC/MS-MS-based metabolomics approach. BMJ open respiratory research 20141 (1), e000056.

    Qin, C.; Yu, C.; Shen, Y.; Fang, X.; Chen, L.; Min, J.; Cheng, J.; Zhao, S.; Xu, M.; Luo, Y. Whole-genome sequencing of cultivated and wild peppers provides insights into Capsicum domestication and specialization. Proceedings of the National Academy of Sciences 2014111 (14), 5135-5140.

    Luan, H.; Meng, N.; Liu, P.; Feng, Q.; Lin, S.; Fu, J.; Davidson, R.; Chen, X.; Rao, W.; Chen, F. Pregnancy-induced metabolic phenotype variations in maternal plasma. Journal of proteome research 201413 (3), 1527-1536.

    Luan, H.; Meng, N.; Fu, J.; Chen, X.; Xu, X.; Feng, Q.; Jiang, H.; Dai, J.; Yuan, X.; Lu, Y. Genome-wide transcriptome and antioxidant analyses on gamma-irradiated phases of Deinococcus radiodurans R1. PloS one 20149 (1), e85649.

    Luan, H.; Chen, X.; Zhong, S.; Yuan, X.; Meng, N.; Zhang, J.; Fu, J.; Xu, R.; Lee, C.; Song, S. Serum metabolomics reveals lipid metabolism variation between coronary artery disease and congestive heart failure: a pilot study. Biomarkers 201318 (4), 314-321.

    Luan, H.-M.; Wang, L.-C.; Wu, H.; Jin, Y.; Ji, J. Antioxidant activities and antioxidative components in the surf clam, Mactra veneriformis. Natural Product Research 201125 (19), 1838-1848.

    Luan, H.; Wang, L.; Hao, W.; Jin, Y.; Chen, S. Determination of Taurine in Mactra Veneriformis by Pre-column Derivatization RP-HPLC. Traditional Chinese Drug Research & Clinical Pharmacology 201021 (02).

     


软件开发
学术论文
  • 暂无内容
专利
  • 暂无内容
著作成果
  • 暂无内容
科研项目
  • 暂无内容