刘旭杰
教师拼音名称:liuxujie
所在单位:生物医药学院
性别:男
联系方式:E-mail: liuxujie@gdut.edu.cn
职称:副教授
在职信息:在职
所属院系:生物医药学院
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科学研究
研究领域
[1] 智能响应型生物材料,包括光/超声/磁场响应生物材料及其在骨科、肿瘤治疗、伤口愈合等领域的综合应用;
[2] 新型药物递送系统的开发及应用,包括纳米药物递送系统、可溶解微针递送系统等;
[3] 人工智能在生物材料领域的应用,AI辅助生物材料设计及性能预测。
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代表性论文成果
- Zhaoyi Ye, Ying Bao, Zefeng Chen, Huiling Ye, Zhenzhen Feng, Yushan Li, Yaoxun Zeng, Zhenxing Pan, Defang Ouyang, Kun Zhang, Xujie Liu*, Yan He*, Recent advances in the metal/organic hybrid nanomaterials for cancer theranostics, Coordination Chemistry Reviews, 2024, 504: 215654 (* Corresponding author).
- Yaoxun Zeng, Zhenxing Pan, Jiongpeng Yuan, Yuqiong Song, Zhenzhen Feng, Zefeng Chen, Zhaoyi Ye, Yushan Li, Ying Bao, Zhili Ran, Xinyi Li, Huiling Ye, Kun Zhang, Xujie Liu*, Yan He*, Inhibiting Osteolytic Breast Cancer Bone Metastasis by Bone-Targeted Nanoagent via Remodeling the Bone Tumor Microenvironment Combined with NIR-II Photothermal Therapy, Small, 2023, 19: 2301003. (* Corresponding author).
- Niping, Chen, Yushan Li, Haihong Li, Yakun Wang, Yaoxun Zeng, Mingxia Zhang, Zhenxing Pan, Zefeng Chen, Wanting Liang, Junhao Huang, Kun Zhang, Xujie Liu*, Yan He*, Multifunctional CuFe2O4@ HA as a GSH-depleting nanoplatform for targeted photothermal/enhanced-chemodynamic synergistic therapy. Colloids and Surfaces B: Biointerfaces, 2023, 229: 113445. (* Corresponding author).
- Siwei Wu, Zhenxing Pan, Xiaojing Li, Yang Wang, Jiacheng Tang, Haishan Li, Guibo Lu, Jianzhong Li, Zhenzhen Feng, Yan He*, Xujie Liu*. Machine learning assisted photothermal conversion efficiency prediction of anticancer photothermal agents." Chemical Engineering Science, 2023, 273: 118619. (* Corresponding author).
- Zhenxing Pan, Yakun Wang, Niping Chen, Guining Cao, Yaoxun Zeng, Jiapeng Dong, Mingzhao Liu, Zhaoyi Ye, Yushan Li, Shun Huang, Yu-jing Lu, Yan He*, Xujie Liu*, Kun Zhang, Aggregation-Induced emission photosensitizer with lysosomal response for photodynamic therapy against cancer, Bioorganic Chemistry, 2023, 132:106349. (* Corresponding author).
- Niping Chen, Yakun Wang, Yaoxun Zeng, Yushan Li, Zhenxing Pan, Haihong Li, Jingman Chen, Zefeng Chen, Jiongpeng Yuan, Wen Yan, Yu-Jing Lu, Xujie Liu*, Yan He*, Kun Zhang, All-in-one CoFe2O4@ Tf nanoagent with GSH depletion and tumor-targeted ability for mutually enhanced chemodynamic/photothermal synergistic therapy. Biomaterials Science, 2023, 11(3): 828-39. (Invited, Emerging Investigator Series).
- Yakun Wang, Niping Chen, Zhenxing Pan, Zhaoyi Ye, Jiongpeng Yuan, Yaoxun Zeng, Wei Long, Wangqing Bian, Xiaojing Li, Yu-Jing Lu, Kun Zhang, Yan He*, Xujie Liu*, A smart small molecule as specific fluorescent probe for sensitive recognition of mitochondrial DNA G-Quadruplexes. Chemical Engineering Journal, 2022, 441: 135977. (* Corresponding author).
- Zefeng Chen, Yaoxun Zeng, Niping Chen, Mingxia Zhang, Yakun Wang, Zhenxing Pan, Jiongpeng Yuan, Zhaoyi Ye, Xiaojing Li, Wangqing Bian, Haihong Li, Kun Zhang, Yan He*, Xujie Liu*, A Facile and Universal Method for Preparing Polyethylene Glycol‐Metal Hybrid Nanoparticles and Their Application in Tumor Theranostics. Advanced Healthcare Materials, 2022, 11: 2200044. (* Corresponding author).
- Jiongpeng Yuan, Zhaoyi Ye, Yaoxun Zeng, Zhenxing Pan, ZhenZhen Feng, Ying Bao, Yushan Li, Xujie Liu*, Yan He*, Qingling Feng*, Bifunctional scaffolds for tumor therapy and bone regeneration: Synergistic effect and interplay between therapeutic agents and scaffold materials. Materials Today Bio, 2022, 15: 100318. (* Corresponding author).
- Wenxia Wang, Tingting Chen, Zhen Li, Qiting Tan, Zhenbang Meng, Hailun Qiu, Xujie Liu* and Junxia Zheng*, Comparison of filtration efficiency and respiratory resistance of COVID-19 protective masks by multi-national standards. American Journal of Infection Control, 2022, 50: 516. (* Corresponding author).
专利
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科研项目
- 国家自然科学基金面上项目,32171314,金纳米笼/噁唑啉等离子体聚合物涂层表面性质结合光热效应抗菌和促成骨的协同作用研究,2022/01-2025/12,58万元,主持,
- 广东省自然科学基金面上项目,2022A1515010671,等离子体聚合构建超声响应的类聚噁唑啉/碲纳米棒表面调控促成骨与抗菌性能,2022/01-2024/12,10万元,主持,
- 广州市基础与应用基础研究项目,202201010371,兼具抗肿瘤效果与骨修复作用的巯基化壳聚糖/Ti基MOF复合支架协同修复骨肿瘤缺损,2022/04-2024/03,5万元,主持,
- 横向项目,阵列式可溶性微针制备技术开发,2023/4-2024/3,5万元,主持,
- 横向项目,Ti基金属-有机框架作为治疗与修复骨肿瘤术后缺损的多功能生物材料的开发与测试,2021/6-2023/12,18万元,主持,
- 先进材料教育部重点实验室开放课题,近红外响应的金纳米笼/噁唑啉等离子体聚合物表面调控促成骨与抗菌性能,2021/6-2021/12,4万元,主持,
- 横向项目,三维多孔抗菌修复膜制备技术开发,2020/12-2022/12,5万元,主持,
- 广东工业大学青年百人计划科研启动经费,纳米药物载体材料与控释系统,2020/05-2024/12,20万,主持,
- 国家自然科学基金青年科学基金项目,31600763,表面形貌梯度和表面化学共同调控细胞行为及相关机理,2017/01-2017/12,10.8万元,主持,
- 中国博士后科学基金特别资助,等离子体聚合构建表面调控细胞成骨分化,2017T100073,15万,主持,