一、部分学术论文

请进入ResearchGate网站查看完整学术发表记录

Jin Fujun#; Liu Meijing#; Zhang Dake*; Wang Xiaogang*; Translational perspective on bone-der ived cytokines in inter-organ communications, The Innovation, 2023, 4(1):100365.

Fujun Jin#, Li Junhui#, Zhang Yong-Biao#, Liu Xiangning#, Cai Mingxiang, Liu Meijing, Li Mengyao, Ma Cui, Yue Rui, Zhu Yexuan, Lai Renfa, Wang Zuolin, Ji Xunming, Wei Huawei, Dong Jun, Liu Zhiduo, Wang Yifei*, Sun Yao*, Wang Xiaogang*. A functional motif of long noncoding RNA Nron against osteoporosis. Nature Communications. 2021; 12.

Delong Song#, Junren Luo#, Xuan Duan, Fujun Jin*, Yu-Jing Lu*. Identification of G- quadruplex nucleic acid structures by high-throughput sequencing: A review. International Journal of Biological Macromolecules, 2025, 297: 139896.

Shimin Lin#, Lishan Zhong#, Jingyi Chen#, Zibo Zhao, Rongze Wang, Yexuan Zhu, Junwei Liu, Yanting Wu, Cuifang Ye*, Fujun Jin*, Zhe Ren*. GDF11 inhibits adipogenesis of human adipose-derived stromal cells through ALK5/KLF15/beta-catenin/PPARgamma cascade. Heliyon, 2023, 9(2):e13088.

Yun Chen, Yuanhui Guo, Bin Xie, Fujun Jin, Li Ma, Hao Zhang, Yihao Li, Xin Chen*, Maoxiang Hou, Jian Gao, Huilong Liu, Yu-Jing Lu*, Ching-Ping Wong, Ni Zhao*. Lightweight and drift-free magnetically actuated millirobots via asymmetric laser-induced graphene. Nature Communications, 2024, 15(1):4334.

Xiao-Chun Guo#, Da-Zhi Shi#, Shun Huang*, Yi-Han Zhang, Wan-Ying Zhang, Jing Chen, Zebin Huang, Hubing Wu, Jin-Qiang Hou, Fu-Jun Jin, Xiu-Cai Chen, Wing-Leung Wong, Yu-Jing Lu*. PET Imaging of Solid Tumors with a G-Quadruplex-Targeting 18F-Labeled Peptide Probe. Journal of Medicinal Chemistry, 2025, 68(3):2804-2814.

Yongyu Xu#, Zebin Huang#, Guangping Wu, Fujun Jin, Shuojia Lin, Chuang Zhang, Jie Zheng, Wenjie Liu, Jinqiang Hou, Yu-Jing Lu*. Bioinformatic assay reveal the potential mechanism of Guizhi-Shaoyao-Zhimu decoction against rheumatoid arthritis and mild-to-moderate COVID-19. Computer Methods and Programs in Biomedicine, 2023, 238:107584.

Jin Fujun#, Zhu Yexuan#, Liu Meijing#, Wang Rongze, Cui Yi, Wu Yanting, Liu Gang, Wang Yifei*, Wang Xiaogang*, Ren Zhe*. Babam2 Negatively Regulates Osteoclastogenesis By Interacting With Hey1 To Inhibit Nfatc1 Transcription. International Journal of Biological Sciences. 2022; 18(11): 4482-4496.

Jin Fujun#, Wang Yiliang#, Wang Xiaojing, Wu Yanting, Wang Xiaoyan, Liu Qiuying, Zhu Yexuan, Liu Enqi*, Fan Jianglin*, Wang Yifei*. Bre enhances osteoblastic differentiation by promoting the Mdm2‐mediated degradation of p53. Stem Cells. 2017; 35: 1760-1772.

Cai Mingxiang#, Xiao Baichuan#, Jin Fujun#, Xu Xiaopeng#, Hua Yuwei, Li Junhui, Niu Pingping, Liu Meijing, Wu Jiaqi, Yue Rui, Zhang Yong, Wang Zuolin*, Zhang Yongbiao*, Wang Xiaogang*, Sun Yao*. Generation of functional oligopeptides that promote osteogenesis based on unsupervised deep learning of protein IDRs. Bone Research. 2022;10(1): 1-13.

Liu Meijing#, Jin Fujun#, Zhang Shuai#, Li Shuang, Zhu Danqi, Cui Yi, Cai Mingxiang, Liu Xiangning, Zhang Yongbiao, Sun Yao*, Liu Changhui*, Wang Xiaogang*. Activation of farnesoid X receptor signaling by geniposidic acid promotes osteogenesis. Phytomedicine. 2022; 103:154258.   

Meijing Liu#, Danqi Zhu#, Fujun Jin#, Shuang Li, Xiangning Liu, Xiaogang Wang*. Peptide modified geniposidic acid targets bone and effectively promotes osteogenesis. Journal of Orthopaedic Translation. 2023; 38: 23-31. 

Shimin Lin#, Lishan Zhong#, Jingyi Chen#, Zibo Zhao, Rongze Wang,Yexuan Zhu, Junwei Liu, Yanting Wu, Cuifang Ye*, Fujun Jin*, Zhe Ren*. GDF11 inhibits adipogenesis of human adipose-derived stromal cells through ALK5/KLF15/β-catenin/PPARγ cascade. Heliyon. 2023.

Jin Fujun#, Zhu Yexuan#, Wang Rongze#, Chen Jingyi, Wang Yiliang, Wu Yanting, Zhou Pengjun, Song Xiaowei, Ren Zhe*, Dong Jun*. BRE Promotes Esophageal Squamous Cell Carcinoma Growth by Activating AKT Signaling. Frontiers in Oncology. 2020; 10: 1407.

Jin Fujun#, Wang Rongze#, Zhu Yexuan#, Chen Jingyi, Cao Wei, Wang Yiliang, Wu Yanting, Song Xiaowei, Huang Yunsheng*, Dong Jun*，Ren Zhe*. A novel quinolinylmethyl substituted ethylenediamine compound exerts anti-cancer effects via stimulating the accumulation of reactive oxygen species and NO in hepatocellular carcinoma cells. European Journal of Pharmacology. 2020: 173497.

Wang Rongze#, Zhu Yexuan#, Chen Jingyi#, Wang Yiliang, Song Xiaowei, Wu Yanting, Jin Fujun *, Wang Yifei * The quinazoline derivative, 04NB-03, induces cell cycle arrest and apoptosis in hepatocellular carcinoma cells in a reactive oxygen species-dependent manner. Chemico-Biological Interactions. 2021; 338: 109371.

Wang Yiliang#, Wang Zhaoyang#, Wang Yun#, Li Feng, Jia Jiaoyan, Song Xiaowei, Qin Shurong, Wang Rongze, Jin Fujun*, Kitazato Kaio*, Wang Yifei*. The Gut-Microglia Connection: Implications for Central Nervous System Diseases. Frontiers in Immunology. 2018; 9: 2325.

Wang Yiliang#, Qin Shurong#, Jia Jiaoyan, Huang Lianzhou, Li Feng, Jin Fujun*, Ren Zhe*, Wang Yifei*. Intestinal Microbiota-Associated Metabolites: Crucial Factors in the Effectiveness of Herbal Medicines and Diet Therapies. Frontiers in Physiology. 2019;10:1343.

Wang Yiliang#, Wang Rongze#, Li Feng, Wang Yun, Zhang Zhen, Wang Qiaoli, Ren Zhe, Fujun Jin*, Kitazato Kaio*, Wang Yifei*. Heat-shock protein 90α is involved in maintaining the stability of VP16 and VP16-mediated transactivation of α genes from herpes simplex virus-1. Molecular Medicine. 2018; 24: 65.

Zhuo Cuiqin#, Zheng Danlin#, He Zhe, Jin Ju, Ren Zhe, Jin Fujun*, Wang Yifei*. HSV-1 enhances the energy metabolism of human umbilical cord mesenchymal stem cells to promote virus infection. Future Virology. 2017; 12: 349-360.

Wang Yiliang#, Jin Fujun#, Wang Rongze, Li Feng, Wu Yanting, Kitazato Kaio*, Wang Yifei*. HSP90: a promising broad-spectrum antiviral drug target. Archives of virology. 2017; 162: 3269-3282.

Wu Yanting#, Jin Fujun#, Wang Yiliang, Li Feng, Wang Lu, Wang Qiaoli, Ren Zhe, Wang Yifei*. In vitro and in vivo anti-inflammatory effects of theaflavin-3, 3′-digallate on lipopolysaccharide-induced inflammation. European Journal of Pharmacology. 2017; 794: 52-60.

Wu Yanting#, Jin Fujun#, Wang Yiliang, Li Feng, Ren Zhe, Wang Yifei*. In vitro and in vivo inhibitory effects of 6-hydroxyrubiadin on lipopolysaccharide-induced inflammation. Immunopharmacology and immunotoxicology. 2017; 39: 107-116.

Wang Yiliang#, Jin Fujun#, Li Feng, Qin Shurong, Wang Yifei*. Could targeting the heat shock protein 90 revolutionize antiviral therapy? Future Virology. 2018; 13: 119-127.

Sun Yao*#, Cai Mingxiang#, Zhong Jiayong#, Yang Li#, Xiao Jia, Jin Fujun, Xue Hui, Liu Xiangning, Liu Huisheng, Zhang Yongbiao, Jiang Dong, Hong An, Ji Xunming, Wang Zuolin*, Zhang Gong*, Wang Xiaogang*. The long noncoding RNA lnc-ob1 facilitates bone formation by upregulating Osterix in osteoblasts. Nature Metabolism. 2019; 1: 485-496.

Li Junhui, Jin Fujun, Cai Mingxiang, Lin Tingting, Wang Xiaogang *, Sun Yao *. LncRNA Nron Inhibits Bone Resorption in Periodontitis. Journal of Dental Research. 2022, 101: 187-195.

Zhang Zhen, Jin Fujun, Wu Zicong, Jin Ju, Li Feng, Wang Yiliang, Wang Zhiping, Tang Shunqing, Wu Chaoxi, Wang Yifei*. O-acylation of chitosan nanofibers by short-chain and long-chain fatty acids. Carbohydrate Polymers. 2017; 177: 203-209.

Wang Rongze#, Zhang Yuanxu#, Jin Fujun, Li Gongchen, Sun Yao*, Wang Xiaogang*. High-glucose-induced miR-214-3p inhibits BMSCs osteogenic differentiation in type 1 diabetes mellitus. Cell death discovery. 2019; 5: 1-11.

Yang Shihua#, Zhang Wenhui#, Cai Mingxiang#, Zhang Yuanxu, Jin Fujun, Yan Sen, Baloch Zulqurain, Fang Zhihao, Xue Senren, Tang Rongping, Xiao Jia, Huang Qunshan, Sun Yao*, Wang Xiaogang*. Suppression of Bone Resorption by miR-141 in Aged Rhesus Monkeys. Journal of Bone and Mineral Research. 2018; 33: 1799-1812.

Zhang Ruilin, Li Junhui, Li Gongchen, Jin Fujun, Wang Zuolin, Yue Rui, Wang Yibin, Wang Xiaogang *, Sun Yao *. LncRNA Nron regulates osteoclastogenesis during orthodontic bone resorption. International Journal of Oral Science. 2020; 12: 14.

二、研究项目

项目负责人，广州市博士启航项目，5万元，2024/01-2025/12。 

项目负责人，国家自然科学基金-面上项目，49万元，2024/01-2027/12。

第二负责人，国家自然科学基金重大研究计划重点项目，250万元，2021/01-2024/12。

项目负责人，企业横向项目，20万元，2023/01-2024/12 。

项目负责人，广东工业大学青年百人科研启动基金，20万，2022/11-2027/11。

项目负责人，国家自然科学基金青年基金项目，21万元，2019/01-2021/12 。

项目负责人，广东省自然科学基金面上项目，10万元，2018/05-2021/04。

项目负责人，中国博士后基金面上项目，8万元，2021/01-2022/06。

项目负责人，中国博士后基金面上项目，5万元，2018/01-2020/06。

三、发明专利

金富军，王史敏，洪哲鑫，宋德龙，黄蝶，卢宇靖；一种具备高破骨细胞分化能力的THP-1细胞、破骨细胞及制备与应用，国内发明专利，专利号ZL 2024 1 0033234.X。

金富军，王晓刚，孙瑶，蔡明详，王一飞；长链非编码RNA NRON功能基序在制备抑制骨吸收及防治骨质疏松药物中的应用，国内发明专利，专利号ZL 20191 1 129088.6，已实现转化。

王晓刚，金富军，刘美静，孙瑶；长链非编码RNA Fmnl1-AS在制备抑制骨吸收药物中的应用，国内发明专利，专利号ZL 2020 1 0414478.4，已实现转化。

王晓刚，金富军，刘美静，孙瑶；长链非编码RNA SNHG12抑制剂在制备对抗骨质疏松药物中的应用，国内发明专利，专利号ZL 2020 1 0418892.2。

王晓刚，金富军，刘美静；长链非编码RNA lnc-ob1在诊断或治疗骨衰老中的应用，国内发明专利，专利号ZL 2022 1 06381660。

金富军，林烁佳，卢宇靖，宋德龙；一种中药组合物在制备通过同时促进骨形成和抑制骨吸收以治疗骨疾病药物中的用途，中国，发明专利，CN 2024 1 0697643.X。

李泽锋，张泽谦，金富军，杨其宇，卢宇靖，周桂涛，洪哲鑫，李飞；一种电容式细胞电刺激通用装置及其应用，中国，发明专利，ZL 2024 1 1603213.3。

陈泽鑫，卢宇靖，金富军，王史敏，洪哲鑫，黄蝶，宋德龙，宋其洲，王玥铭，郑伯鑫，罗竣仁；一种通过荧光成像检测单基因RNA G4的试剂、方法及其应用，中国，发明专利，CN 2025 1 00381694。

张思绮，陈修财，金富军，卢宇靖；一种具有光电二重性的银-钠离子材料及其制备方法和应用，中国，发明专利，ZL 2024 1 0591465.2。

郭晓纯，卢宇靖，张艺瀚，陈修财，金富军，方志远；一种检测核酸胞嘧啶脱氨酶APOBEC3B活性的化学发光试剂盒及其应用，中国，发明专利，ZL 2024 1 0232370。