何燕
硕士生导师
教师拼音名称：heyan
职称：副教授
所属院系：生物医药学院
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科学研究
研究领域
[1] 药物新剂型和制剂新技术：缓控释制剂；抗肿瘤纳米靶向系统设计；有机光热小分子的合成与抗肿瘤光热疗法.
[2] 中药经典名方研究：数据挖掘；中成药制剂工艺研究；标准与质量研究；活性评价.
[3] 人工智能在药物研发中的应用.
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代表性论文
- Siwei Wu, Zhenxing Pan, Xiaojing Li, Yang Wang, Jiacheng Tang, Haishan Li, Guibo Lu, Jianzhong Li, Zhenzhen Feng, Yan He*, Xujie Liu*. Machine Learning Assisted Photothermal Conversion Efficiency Prediction of Anticancer Photothermal Agents. Chemical Engineering Science, 2023: 118619. (SCI, IF=4.889, II区, 通讯作者).
- Zhenxing Pan, Yakun Wang, Niping Chen, Guining Cao, Yaoxun Zeng, Jiapeng Dong, Mingzhao Liu, Zhaoyi Ye, Yushan Li, Shun Huang, Yu-jing Lu, Xujie Liu*, Yan He*, Kun Zhang. Aggregation-Induced Emission Photosensitizer with Lysosomal Response for Photodynamic Therapy Against Cancer. Bioorganic Chemistry, 2023, 132: 106349. (SCI, IF=5.307, I区, 通讯作者).
- Niping Chen, Yakun Wang, Yaoxun Zeng, Yushan Li, Zhenxing Pan, Haihong Li, Jingman Chen, Zefeng Chen, Jiongpeng Yuan, Wen Yan, Yu-Jing Lu, Xujie Liu*, Yan He*, Kun Zhang. All-In-One CoFe(2)O(4)@Tf Nanoagent with GSH Depletion and Tumor-Targeted Ability for Mutually Enhanced Chemodynamic/Photothermal Synergistic Therapy. Biomaterials Science, 2023, 11(3): 828-839. (SCI, IF=7.59, II区, 通讯作者).
- Jiongpeng Yuan, Zhaoyi Ye, Yaoxun Zeng, Zhenxing Pan, ZhenZhen Feng, Ying Bao, Yushan Li, Xujie Liu*, Yan He*, Qingling Feng. Bifunctional Scaffolds for Tumor Therapy and Bone Regeneration: Synergistic Effect and Interplay Between Therapeutic Agents and Scaffold Materials. Materials Today Bio, 2022, 15: 100318. (SCI, IF=10.761, I区, 通讯作者).
- Yakun Wang, Niping Chen, Zhenxing Pan, Zhaoyi Ye, Jiongpeng Yuan, Yaoxun Zeng, Wei Long, Wangqing Bian, Xiaojing Li, Yujing Lu, Kun zhang, Yan He*, Xujie Liu*. A Smart Small Molecule as Specific Fluorescent Probe for Sensitive Recognition of Mitochondrial DNA G-Quadruplexes. Chemical Engineering Journal, 2022, 441: 135977. (SCI, IF=16.744, I区, 通讯作者).
- Zefeng Chen1§, Yaoxun Zeng1§, Niping Chen, Mingxia Zhang, Yakun Wang, Zhenxing Pan, Jiongpeng Yuan, Zhaoyi Ye, Xiaojing Li, Wangqing Bian, Haihong Li, Kun Zhang, Yan He*, Xujie Liu*. A Facile and Universal Method for Preparing Polyethylene glycol-Metal Hybrid Nanoparticles and Their Application in Tumor Theranostics. Advanced Healthcare Materials, 2022, 11(12): 2200044. (SCI, IF=11.092, I区, 通讯作者).
- Wangqing Bian, Zhenxing Pan, Yakun Wang, Wei Long, Zefeng Chen, Niping Chen, Yaoxun Zeng, Jiongpeng Yuan, Xujie Liu, Yujing Lu, Yan He*, Kun Zhang*. A Mitochondria-Targeted Thiazoleorange-Based Photothermal Agent for Enhanced Photothermal Therapy for Tumors. Bioorganic Chemistry, 2021, 113: 104954. (SCI, IF=5.307, I区, 通讯作者).
- Xujie Liu, Yakun Wang, Yan He*, Xiaofeng Wang*, Ranran Zhang, Akash Bachhuka, Rahul Madathiparambil Visalakshan, Qingling Feng, Krasimir Vasilev. Synergistic Effect of Surface Chemistry and Surface Topography Gradient on Osteogenic/Adipogenic Differentiation of hMSCs. ACS Applied Materials & Interfaces, 2021, 13(26): 30306-30316. (SCI, IF=10.383, I区, 通讯作者).
- Wangqing Bian, Yakun Wang, Zhenxing Pan, Niping Chen, Xiaojing Li, Wing-Leung Wong, Xujie Liu, Yan He*, Kun Zhang, Yu-Jing Lu*. Review of Functionalized Nanomaterials for Photothermal Therapy of Cancers. ACS Applied Nano Materials, 2021, 4(11): 11353-11385. (SCI, IF=6.140, II区, 通讯作者).
- Yan He, Hongfei Liu, Wangqing Bian, Yue Liu, Xinyang Liu, Shijing Ma, Xi Zheng, Zhiyun Du, Kun Zhang, Defang Ouyang. Molecular Interactions for the Curcumin-Polymer Complex with Enhanced Anti-Inflammatory Effects. Pharmaceutics, 2019, 11(9): 442. (SCI, IF=6.525 II区, 第一作者).
代表性授权专利
- 张日威，何燕，蔡述庭，熊晓明，郭靖.一种用于全髋关节置换手术的虚拟学习方法[P].ZL202110126745.2, 2023-01-20.
- 张日威，何燕，蔡述庭，熊晓明，张子睿，滕潇，曹帆，徐瑶通.一种中药/天然植物提取的数学建模方法[P].ZL202010461973.0,2022-07-05.
- 卞旺青，何燕，卢宇靖，龙威，张焜，张智，陈泽丰，王亚坤，陈霓平，黄艺斌.一种化合物及其制备方法、荧光探针和抗肿瘤药物[P].ZL202010630922.6,2022-07-12.
- 曹帆，何燕，陈学松，蔡述庭，熊晓明，滕潇，徐瑶通，张日威，张子睿.一种应用于中药提取浓缩工艺的增强现实系统[P].ZL202010707100.3,2022-07-05.
- 卞旺青，何燕，卢宇靖，龙威，张焜，张智，陈泽丰，王亚坤，陈霓平，黄艺斌.一种化合物和纳米胶束[P].ZL202010631376.8,2021-11-26.
- 武文敬，何燕，梁立尹，易如婷，蔡浛，张焜.一种簕菜提取物的新用途[P].ZL201810311312.2,2021-05-11.
- 马诗经，杜志云，何燕，吕惠彬，张焜，李晨悦，梁学良，钟燕琼，刘美祺，郑希，艾伦·康尼.一种姜黄素保健颗粒剂及其制备方法[P].ZL201310122934.8,2015-01-07.
- 杜志云，何燕，马诗经，吕惠彬，梁学良，钟燕琼，刘美祺，张焜，李晨悦，郑希，艾伦·康尼.一种姜黄素和沙棘组成的保健饮料及其制备方法[P].ZL201310121024.8,2014-08-13.
