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陈新

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  •  硕士生导师
  • 电子邮箱:
  • 所在单位:自动化学院
  • 性别:女
  • 学位:理学博士学位
  • 在职信息:在职
  • 所属院系:自动化学院

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  • 个人简介

陈新,博士,硕士研究生导师。20168月由广东工业大学“青年百人”人才计划引进,广东省物联网重点实验室、广东工业大学智能信息处理研究所成员。长期从事数据分析、组学大数据、大规模生物分子网络调控、肿瘤分子标志物相关研究。近期研究兴趣包括:1) 单细胞复杂转录调控网络角度下的细胞异质性研究; 2) 肿瘤预后相关新型分子标志物的识别; 3) 分子标志物相关数据库建设。目前已发表论文20余篇,申请发明专利4项,主持国家自然科学青年项目1项、广东省自然科学基金面上项目2项,广州市基础与应用基础研究项目1项,并作为主要参与人参加多项国家级及省部级项目。

欢迎对大数据、机器学习、深度学习感兴趣的研究生与本科实习生加入课题组。

科研项目

[1] 基于单细胞ceRNA网络的乳腺癌细胞异质性研究, 国家自然科学基金青年基金,批准号:62003094 24万, 2021.012023.12.

[2] 基于单细胞转录后调控ceRNA网络的乳腺癌瘤内细胞异质性研究, 广州市基础与应用基础研究项目(博士青年科技人员类)

项目编号:202102020573 5 2021.04—2023.03.

[3] 基于多组学大数据和临床信息优选乳腺癌的预后标记, 广东省自然科学基金面上项目, 批准号:2019A151501137710万,2019.10-2022.09.

[4] 基于多来源转录组大数据和临床病理信息识别乳腺癌的预后标志物,广东省自然科学基金面上项目, 批准号:2018A0303130080 10万,

2018.052021.04.

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发表论文


[1] Hu L#, Chen X#, Narwade N#, Lim M, Chen Z, Tennakoon C, Guan P, Chan U, Zhao Z, Deng M, Xu X, Sung W*, and Cheung E*. Single-Cell Analysis Reveals Androgen Receptor Regulates the ER-to-Golgi Trafficking Pathway with CREB3L2 to Drive Prostate Cancer Progression, Oncogene, 2021. (co-first, Nature子刊,SCI 1区, TOP期刊,IF=9.87) 

[2] Zhang H, Shao Y, Chen W, and Chen X*. Identifying mitochondrial related genes NDUFA10 and NDUFV2 as prognostic markers for prostate cancer through biclustering, BioMed Research International, 2021, 2021:5512624. (SCI 3区, IF=3.41)

[3] Chen  X#, Xu J#, Zeng F, Yang C, Sun Wei, Yu T and Li Y*. Inferring Cell Subtypes and LncRNA Function by Cell Specific CeRNA Network in Breast Cancer, Frontiers in Oncology, 2021, 11:656675. (SCI 2, IF=6.24)

[4] Zhang W, Chen X, Sun W, Nie T, Quanquin N, Sun Y*. Escherichia Coli Increases its ATP Concentration in Weakly Acidic Environments Principally through the Glycolytic Pathway, Genes (Basel), 2020, 11(9):991. (SCI 3, IF=3.33)

[5] Chen X, Hu L, Wang Y, Sun W and Yang C*. Single Cell Gene Co-Expression Network Reveals FECH/CROT Signature as a Prognostic Marker, Cells, 2019, 8(7). (SCI 2, IF=4.37)

[6] Yang C, Chen X*, Liu Y, Zhong W, Xie, S. Efficient Task Offloading and Resource Allocation for Edge Computing-Based Smart Grid Networks, IEEE Access, 2019, 7(7). (SCI 2, IF=4.09)

[7] Mo W, Yang C*, Chen X, Lin K, Duan S. Optimal Charging Navigation Strategy Design for Rapid Charging Electric Vehicles, Energies, 2019, 12(6). (SCI 3, IF=2.71)

[8] Verma A, Lam Y, Leung Y, Hu X, Chen X, Cheung E, Tam K. Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells, J Pharm Pharmacol, 2019, 71(3):306-315. (SCI 3, IF:2.57)

[9] Yang C, Chen X, Liu Y, Zhong W, Xie S*. Efficient Task Offloading and Resource Allocation for Edge Computing-Based Smart Grid Networks, 2019 IEEE International Conference on Communications, ICC 2019. (EI检索会议)

[10] Chen X, Miao Z, Divate M, Zhao Z and Cheung E*. KM-Express: An integrated online patient survival and gene expression analysis tool for the identification and functional characterization of prognostic markers in breast and prostate cancers, Database (Oxford), 2018, doi: 10.1093/database/bay069. (SCI 3, IF: 3.98)

[11] Chen X, Yang Z, Yang C, Xie K, Sun W, and Xie S*. Sparse Gene Coexpression Network Analysis Reveals EIF3J-AS1 as a Prognostic Marker for Breast Cancer, Complexity, 2018, doi: 10.1155/2018/1656273. (SCI 2, IF: 4.62)

[12] Yan L, Jiang B, Li E, Wang X, Ling Q, Zheng D, Woo J, Chen X, Cheung E, Du X, Li Y, Cheng G, He E, Xu R*. Scalable Generation of Mesenchymal Stem Cells from Human Embryonic Stem Cells in 3D, International Journal of Biological Sciences, 2018, 14(10):1196-1210. (SCI 2, IF: 4.86)

[13] Lingadahalli S, Jadhao S, Sung YY, Chen M, Hu L, Chen X, Cheung E*. Novel lncRNA LINC00844 Regulates Prostate Cancer Cell Migration and Invasion Through AR Signaling, Mol Cancer Res, 2018, 16(12):1865-1878. (SCI 2, IF: 4.6)

[14] Zhu D#, Zhao Z#, Cui G, Chang S, Hu L, See Y, Lim M, Guo D, Chen X, Robson P, Luo Y, Cheung E*. Single-Cell Transcriptome Analysis Reveals Estrogen Signaling Coordinately Augments One- Carbon, Polyamine, and Purine Synthesis in Breast Cancer, Cell Reports, 2018, 25(8): 2285-2298. (SCI 1, IF: 8.03)

[15] Su Z, Zhang Y, Liao B, Zhong X, Chen X, Wang H, Guo Y, Shan Y, Wang L, Pan G*. Antagonism between the transcription factors NANOG and OTX2 specifies rostral or caudal cell fate during neural patterning transition, J Biol Chem, 2018, 293(12):4445-4455. (SCI 2, IF:4.01)

[16] Chen X, Yang C, Xie S, Cheung E*. Long non-coding RNA GAS5 and ZFAS1 are prognostic markers involved in translation targeted by miR-940 in prostate cancer, Oncotarget, 2017, 9(1): 1048-1062. (SCI 2, IF: 5.62)

[17] Huang K, Du J, Ma N, Liu J, Wu P, Dong X, Meng M, Wang W, Chen X, Shi X, Chen Q, Yang Z, Chen S, Zhang J, Li Y, Li W, Zheng Y, Cai J, Li P, Sun X, Wang J, Pei D*, Pan G*. GATA2(-/-) human ESCs undergo attenuated endothelial to hematopoietic transition and thereafter granulocyte commitment, Cell Regeneration, 2015, 4(1):4. (SCI 4, IF: 0.26)

[18] Li Y#, Li W#, Chen X#, Jiang H, Sun J, Chen H, Lv S*. Integrated analysis identifies interaction patterns between small molecules and pathways. Biomed Research International, 2014, 2014: 931825. (co-first, SCI 3, IF:2.19)

[19] Li Y , Huang T , Xiao Y, Ning S, Wang P, Wang Q, Chen X, Chaohan X, Sun D, Li X, Li Y*. Prioritising risk pathways of complex human diseases based on functional profiling, European Journal Human Genetics, 2013, 21(6): 666-72. (SCI 2, IF: 4.23)

[20] Chen X#, Jiang W#, Wang Q, Huang T, Wang P, Li Y, Lv Y, Li X*. Systematically characterizing and prioritizing chemosensitivity related gene based on Gene Ontology and protein interaction network, BMC Medical Genomics, 2012, 5(1):43. (SCI 3, IF:3.47)

[21] Lv S#, Xu Y#, Chen X#, Li Y, Li R, Wang Q, Li X*, Su B*. Prioritizing Cancer Therapeutic Small Molecules by Integrating Multiple OMICS Datasets, OMICS-A Journal of Integrative Biology, 2012, 16(10):552-559. (co-first, SCI 3, IF:2.73)


  • 社会兼职
  • 研究方向
  • 工作经历
  • 教育经历
  • 2014/5~2016/9

    澳门大学健康科学学院 | 博士后研究员

  • 2013/1~2014/5

    中国科学院广州生物医药与健康研究院 | 助理研究员

  • 2007/9~2012/6

    哈尔滨医科大学  | 生物物理学  | 理学博士学位

  • 2003/9~2007/6

    武汉工程大学  | 电子信息工程  | 工学学士学位